Report Delivery Time: 3 Days
Recommended Gender: Both
Sample Type: Blood
The HLA-B27 PCR test detects the presence of the HLA-B27 gene, which is associated with autoimmune disorders such as ankylosing spondylitis and reactive arthritis. It helps doctors assess genetic risk factors for inflammatory conditions.
₹3,000.00
+919354028488
Email Address
info@hprimelabs.com
Email Address
customercare@hprimelabs.com
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An HLA B27 Test by RT PCR detects the HLA B27 gene to assess the risk of autoimmune diseases like ankylosing spondylitis. It is a specific human leukocyte antigen (HLA) found on the surface of white blood cells. Its presence is linked to certain autoimmune diseases, particularly those affecting the joints and spine. The polymerase chain reaction (PCR) method provides highly accurate detection of this gene.
Why is the HLA B27 Test By RT PCR Done?
- To help diagnose ankylosing spondylitis and other spondyloarthropathies.
- To assess genetic predisposition to autoimmune disorders.
- To differentiate autoimmune arthritis from other joint diseases.
- To evaluate unexplained chronic back pain and inflammation.
Who Should Get This Test?
- Individuals with persistent lower back pain and stiffness.
- Those with a family history of HLA-B27-related diseases.
- Patients with unexplained joint pain, eye inflammation (uveitis), or skin conditions linked to autoimmune disorders.
- People experience symptoms of reactive arthritis, inflammatory bowel disease, or psoriatic arthritis.
Test Procedure & Preparation:
- Sample Required: Blood sample from a vein.
- Preparation: No special preparation is needed.
- Test Duration: Results are available within a few days.
Understanding the Results:
- Positive HLA-B27: Indicates a genetic predisposition to autoimmune diseases but does not confirm a disease diagnosis. Further clinical evaluation is needed.
- Negative HLA-B27: Suggests a lower likelihood of having HLA-B27-related conditions but does not rule them out completely.
This test helps in diagnosing autoimmune disorders early, allowing timely management and treatment.
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