Report Delivery Time: Same Day
Recommended Gender: Both
Sample Type: Blood
The dsDNA test detects anti-double stranded DNA (anti-dsDNA) antibodies, which are primarily associated with autoimmune diseases like systemic lupus erythematosus (SLE). It helps confirm lupus diagnosis and monitor disease progression. This test is recommended for individuals experiencing persistent fatigue, joint pain, skin rashes, or kidney issues.
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The dsDNA (Anti-Double Stranded DNA) ELISA test is a highly specific diagnostic test used to detect autoantibodies that attack the body’s DNA. These antibodies are strongly linked to systemic lupus erythematosus (SLE), an autoimmune disease that affects multiple organs, including the skin, joints, kidneys, and heart.
Why is the Test Done?
This test is performed to:
- Diagnose systemic lupus erythematosus (SLE).
- Differentiate lupus from other autoimmune diseases.
- Monitor lupus activity and assess treatment effectiveness.
- Evaluate kidney involvement in lupus (lupus nephritis).
Who Should Get This Test?
This test is recommended for individuals with symptoms of autoimmune disease, including:
- Unexplained fatigue and muscle weakness.
- Joint pain, swelling, or stiffness.
- A butterfly-shaped rash on the face.
- Kidney problems or abnormal urine test results.
Test Procedure & Preparation
- A blood sample is drawn from a vein.
- No fasting is required.
- Certain medications (such as immunosuppressants) may affect results, so inform your doctor about any ongoing treatments.
Understanding the Results
- Positive dsDNA Test: Strongly indicates lupus, especially in high concentrations.
- Negative dsDNA Test: This usually means lupus is unlikely, but further testing may be needed.
- Moderate Levels: This may indicate another autoimmune disorder or an early stage of lupus.
This test is crucial for confirming lupus and guiding appropriate treatment.
