Report Delivery Time: Next Day
Recommended Gender: Both
Sample Type: Blood
The Bile Acid Test measures the levels of bile acids in the blood to assess liver function and bile metabolism. It is primarily used to diagnose cholestasis (reduced bile flow), liver diseases, and intrahepatic cholestasis of pregnancy (ICP).
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The Bile Acid Test is a diagnostic blood test that evaluates the liver’s ability to process and regulate bile acids. Bile acids are essential for fat digestion and absorption and are produced by the liver. This test is commonly used to detect liver disorders, bile flow obstruction, and pregnancy-related liver conditions like intrahepatic cholestasis of pregnancy (ICP).
Why is the Bile Acid Test Done?
✔ To assess liver function and detect liver diseases.
✔ To diagnose intrahepatic cholestasis of pregnancy (ICP), which can cause severe itching and complications during pregnancy.
✔ To monitor bile metabolism in patients with known liver or gallbladder disorders.
✔ To evaluate bile acid malabsorption and digestive disorders.
Who Should Get This Test?
📌 Pregnant women experiencing severe itching (especially on hands and feet) – To check for ICP.
📌 Individuals with symptoms of liver disease, such as:
- Jaundice (yellowing of skin and eyes).
- Fatigue and weakness.
- Dark urine and pale stool.
- Persistent nausea and loss of appetite.
📌 People with suspected bile acid malabsorption, which can lead to chronic diarrhea.
📌 Patients with gallbladder diseases or bile duct obstructions.
How is the Bile Acid Test Performed?
Preparation:
- Fasting for 12 hours before the test may be required.
- Avoid alcohol and high-fat meals before the test.
Procedure:
- A blood sample is drawn from a vein in the arm.
- The sample is analyzed using spectrophotometry.
- Results are usually available within 24-48 hours.
Understanding the Results
| Bile Acid Level | Possible Indications |
|---|---|
| Normal Range (0-10 µmol/L) | Healthy bile metabolism |
| Mildly Elevated Levels | Early liver dysfunction, mild cholestasis |
| Significantly High Levels | Liver disease, intrahepatic cholestasis of pregnancy (ICP), bile duct obstruction |
⚠ Elevated bile acid levels may indicate:
- Liver diseases (hepatitis, cirrhosis, fatty liver disease).
- Intrahepatic cholestasis of pregnancy (ICP) – A liver disorder that occurs during pregnancy.
- Bile duct obstruction due to gallstones or tumors.
- Bile acid malabsorption leads to chronic diarrhea and nutritional deficiencies.
Conditions Associated with High Bile Acid Levels
📌 Intrahepatic Cholestasis of Pregnancy (ICP) – A pregnancy-related liver condition that can cause severe itching and complications for the baby.
📌 Liver Diseases – Including hepatitis, cirrhosis, and fatty liver disease.
📌 Bile Duct Obstruction – Blockage due to gallstones or tumors.
📌 Bile Acid Malabsorption – A digestive disorder leading to chronic diarrhea.
Limitations of the Test
❌ Not a standalone diagnostic test for liver disease – Additional liver function tests may be required.
❌ Levels can be influenced by diet, requiring fasting for accurate results.
❌ Does not pinpoint the exact cause of bile acid elevation, so further testing may be needed.
Why is the Bile Acid Test Important?
✔ Helps diagnose liver and bile duct diseases early.
✔ Essential for detecting intrahepatic cholestasis of pregnancy (ICP), which can affect fetal health.
✔ Aids in identifying bile acid malabsorption and digestive disorders.
The Bile Acid Test plays a crucial role in evaluating liver function, diagnosing pregnancy-related liver conditions, and detecting bile metabolism disorders.
