CA -125 (Ovarian Cancer Marker) Test
Report Delivery Time: Next Day
Recommended Gender: Female
Sample Type: Blood
The CA-125 (Ovarian Cancer Marker) Test measures the levels of cancer antigen 125 (CA-125), a protein found in the blood. It is primarily used to monitor ovarian cancer, detect recurrence, and evaluate treatment response. It may also be elevated in non-cancerous conditions like endometriosis, pelvic inflammatory disease, and pregnancy.
₹1,200.00
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The CA-125 Test is a blood test that detects the levels of cancer antigen 125 (CA-125), a protein that is often elevated in ovarian cancer. While it is not a definitive diagnostic test, it is an essential tool for monitoring cancer progression, detecting recurrence, and assessing treatment effectiveness.
Important Note: CA-125 levels can also rise due to non-cancerous conditions like menstruation, pregnancy, or endometriosis, so it is not solely used for ovarian cancer diagnosis.
Why is the CA-125 Test Done?
✔ To monitor ovarian cancer progression in diagnosed patients.
✔ To check for recurrence after ovarian cancer treatment.
✔ To evaluate the effectiveness of ongoing cancer treatment.
✔ To support diagnosis in women at high risk of ovarian cancer (in combination with other tests like ultrasound and biopsy).
✔ To investigate unexplained pelvic pain, bloating, or other gynecological symptoms.
Who Should Get This Test?
📌 Women diagnosed with ovarian cancer to track treatment response.
📌 Women with a family history of ovarian cancer (especially with BRCA1 or BRCA2 mutations).
📌 Patients with persistent symptoms like:
- Abdominal or pelvic pain.
- Bloating and feeling full quickly.
- Unexplained weight loss.
- Frequent urination.
📌 Doctors may also use this test in combination with imaging tests for suspected ovarian cancer cases.
How is the CA-125 Test Performed?
Preparation:
- No fasting is required.
- Inform your doctor about any medications or menstrual cycle status.
Procedure:
- A blood sample is drawn from a vein in the arm.
- The sample is analyzed using CLIA (Chemiluminescent Immunoassay).
- Results are usually available within 24-48 hours.
Understanding the Results
| CA-125 Level | Possible Indications |
|---|---|
| Normal Range (Less than 35 U/mL) | No significant concern |
| Elevated Levels (Above 35 U/mL) | Possible ovarian cancer, but could also be due to non-cancerous conditions |
| Significantly High Levels | More likely linked to advanced ovarian cancer or other malignancies |
⚠ Elevated CA-125 levels are not always due to cancer! They can also occur due to:
- Endometriosis
- Pelvic inflammatory disease (PID)
- Uterine fibroids
- Pregnancy
- Liver disease
Conditions Associated with High CA-125 Levels
📌 Ovarian Cancer – The primary reason for measuring CA-125 levels.
📌 Endometriosis – A condition where uterine tissue grows outside the uterus.
📌 Pelvic Inflammatory Disease (PID) – A bacterial infection affecting the female reproductive organs.
📌 Peritonitis – Inflammation of the abdominal lining.
📌 Liver Diseases – Such as hepatitis and cirrhosis.
Limitations of the Test
❌ Not a standalone diagnostic test for ovarian cancer – Requires imaging and biopsy for confirmation.
❌ Levels can be elevated in benign conditions, leading to false positives.
❌ Low CA-125 levels do not rule out ovarian cancer, as some tumors do not produce this protein.
Why is the CA-125 Test Important?
✔ Crucial for monitoring ovarian cancer progression and recurrence.
✔ Helps in early detection in high-risk patients (when used with imaging).
✔ Aids in evaluating treatment success in ovarian cancer patients.
The CA-125 (Ovarian Cancer Marker) Test is an essential tool for cancer monitoring and risk assessment, but it should always be used alongside other diagnostic methods for accurate interpretation.
