C3- Complement 3 Test
Report Delivery Time: Next Day
Recommended Gender: Both
Sample Type: Blood
The C3 Complement Test measures the levels of Complement 3 (C3), a protein in the immune system that helps fight infections. This test is used to diagnose immune system disorders, autoimmune diseases, and infections such as lupus, rheumatoid arthritis, and recurrent bacterial infections.
₹600.00
+919354028488
Email Address
info@hprimelabs.com
Email Address
customercare@hprimelabs.com
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The C3 Complement Test evaluates the levels of Complement 3 (C3) in the blood. C3 is a crucial part of the complement system, a group of proteins that help the immune system defend against pathogens and clear damaged cells. Low or high levels of C3 may indicate autoimmune disorders, infections, or inflammatory diseases.
Why is the C3 Complement Test Done?
✔ To diagnose autoimmune diseases like systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA).
✔ To monitor disease activity in people with known autoimmune conditions.
✔ To detect immune system deficiencies, which can cause frequent infections.
✔ To evaluate complement system function in cases of chronic inflammation.
Who Should Get This Test?
📌 People with symptoms of autoimmune diseases, such as:
- Fatigue, joint pain, and swelling (common in lupus and RA).
- Skin rashes, especially butterfly rash on the face (sign of lupus).
- Persistent infections or unexplained inflammation.
📌 Individuals with chronic infections that do not respond to treatment.
📌 Those with a family history of complement system disorders.
How is the C3 Complement Test Performed?
Preparation:
- No special preparation is required.
- A doctor may advise avoiding certain medications that affect immune function.
Procedure:
- A blood sample is drawn from a vein in the arm.
- The sample is analyzed using Nephelometry, a technique to measure protein concentration.
- Results are typically available within 24-48 hours.
Understanding the Results
| C3 Levels | Possible Indications |
|---|---|
| Normal Range | 75-175 mg/dL |
| Low C3 Levels | Autoimmune diseases (Lupus, RA), chronic infections, complement deficiencies |
| High C3 Levels | Acute or chronic inflammation, infections, cancer |
⚠ Low C3 levels are a strong indicator of active lupus or other autoimmune conditions.
Conditions Associated with Abnormal C3 Levels
📌 Low C3 Levels:
- Systemic Lupus Erythematosus (SLE) – C3 is consumed due to excessive immune activation.
- Rheumatoid Arthritis (RA) – Inflammatory processes reduce complement levels.
- Chronic infections – Tuberculosis, bacterial sepsis, and viral infections.
- Hereditary complement deficiencies – Genetic conditions causing recurrent infections.
📌 High C3 Levels:
- Acute inflammation from infections or trauma.
- Certain cancers such as leukemia or lymphoma.
- Metabolic syndrome and cardiovascular diseases.
Limitations of the Test
❌ Cannot diagnose a specific disease but helps in assessing immune activity.
❌ C3 levels alone are not enough; doctors may order a C4 Complement Test for a complete immune evaluation.
❌ Medications like corticosteroids and immunosuppressants may alter results.
Why is the C3 Complement Test Important?
✔ Helps in early diagnosis and monitoring of autoimmune diseases.
✔ Provides insight into immune system health and infection risks.
✔ Guides treatment decisions in inflammatory and immune-related conditions.
The C3 Complement Test is a crucial diagnostic tool for autoimmune diseases, chronic infections, and immune deficiencies, ensuring timely medical intervention and effective disease management.
